Liposomal doxorubicin

Name: Liposomal doxorubicin
Brand: JEEDNYA PHARMA
Price: 9400 INR
Availability: InStock

9400 INR/Vial

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Product Details:

Salt Composition Doxorubicin Hydrochloride (Liposome-encapsulated)
Indication Ovarian cancer, multiple myeloma, breast cancer, AIDS-related Kaposis sarcoma, metastatic cancers
Dosage Form Sterile injectable suspension
Feature PEGylated liposomal formulation for reduced cardiotoxicity and enhanced tumor targeting
Ingredients Doxorubicin Hydrochloride, Hydrogenated Soy Phosphatidylcholine, Cholesterol, Methoxy Polyethylene Glycol DSPE, Sucrose, Ammonium Sulfate, Water for Injection
Application Antineoplastic/anticancer agent, intravenous administration
Ph Level Approximately 7.0
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Liposomal doxorubicin Price And Quantity

Minimum Order Quantity 100 Vial
Price 9400 INR/Vial

Liposomal doxorubicin Product Specifications

Fermentation Smell Odorless
Dosage Form Sterile injectable suspension
Ingredients Doxorubicin Hydrochloride, Hydrogenated Soy Phosphatidylcholine, Cholesterol, Methoxy Polyethylene Glycol DSPE, Sucrose, Ammonium Sulfate, Water for Injection
Indication Ovarian cancer, multiple myeloma, breast cancer, AIDS-related Kaposis sarcoma, metastatic cancers
Physical Color/Texture Red, sterile, opaque liposomal suspension
Feature PEGylated liposomal formulation for reduced cardiotoxicity and enhanced tumor targeting
Shelf Life 24 months (from date of manufacture)
Salt Composition Doxorubicin Hydrochloride (Liposome-encapsulated)
Ph Level Approximately 7.0
Storage Instructions Store at 2C to 8C (Refrigerate, do not freeze)
Application Antineoplastic/anticancer agent, intravenous administration

Product Description

Liposomal Doxorubicin is an innovative chemotherapy medication encapsulated within lipid-based nanoparticles, enhancing its effectiveness and safety profile. Used in the treatment of various cancers, including ovarian cancer, and Kaposi's sarcoma, Liposomal Doxorubicin delivers the medication directly to cancer cells while minimizing damage to healthy tissues. This targeted approach reduces side effects commonly associated with traditional chemotherapy, such as hair loss and nausea. Administered intravenously under medical supervision, Liposomal Doxorubicin offers patients a potent treatment option with improved tolerability and better outcomes, providing hope and relief in the fight against cancer.

Targeted Anticancer Efficacy

This advanced liposomal doxorubicin formulation is specifically designed to enhance drug delivery to tumor cells while minimizing exposure to healthy tissues. Utilizing PEGylated liposomes, it allows for reduced cardiotoxicity compared to conventional doxorubicin, making it particularly beneficial for patients requiring long-term therapy. Its effectiveness in treating various types of cancers, including ovarian cancer and Kaposi's sarcoma, is well documented.

Safe Handling and Storage Guidelines

Proper storage and handling are vital. Store liposomal doxorubicin between 2C and 8C in its original carton, protected from light. The product should not be frozen. Upon opening, use immediately and discard any unused portion. Always handle with gloves and protective equipment as per cytotoxic chemotherapy protocols to ensure safety for healthcare professionals.

FAQ's of Liposomal doxorubicin:

Q: How should liposomal doxorubicin be administered?

A: Liposomal doxorubicin is intended exclusively for intravenous infusion. It should be diluted only with 0.9% Sodium Chloride Injection, as using dextrose solutions is incompatible. The infusion should be performed in a controlled clinical setting following standard chemotherapy safety protocols.

Q: What cancers is liposomal doxorubicin approved to treat?

A: This formulation is indicated for a range of cancers, including ovarian cancer, breast cancer, multiple myeloma, metastatic cancers, and AIDS-related Kaposi's sarcoma. Its enhanced targeting profile makes it suitable for these conditions where conventional doxorubicin may pose higher risks.

Q: When should the vial be used after opening?

A: Once opened, liposomal doxorubicin must be used immediately. Any unused portion should be promptly discarded to maintain safety and drug effectiveness.

Q: Where should this medication be stored before use?

A: The vials should be kept refrigerated at 2C to 8C in their original light-protective packaging. Do not freeze the product, and avoid transferring it to other containers prior to use.

Q: What are the main safety precautions during handling and preparation?

A: Due to its cytotoxic nature, liposomal doxorubicin must be handled with appropriate safety equipment such as gloves and protective gowns. Preparation should follow established chemotherapy safety protocols to prevent occupational exposure.

Q: What benefits does the liposomal formulation provide compared to conventional doxorubicin?

A: The PEGylated liposomal formulation offers reduced cardiotoxicity and enhanced tumor targeting. This allows higher cumulative doses and sustained efficacy, delivering doxorubicin more specifically to cancer cells while sparing healthy tissues.

Q: How is liposomal doxorubicin different from conventional doxorubicin?

A: Unlike conventional doxorubicin, this product is suspended in a sterile, red, opaque liposomal solution with nanometer-scale particles. Substitution is not recommended, as formulations differ significantly in dosing, safety profile, and clinical use.