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Pemetrexed Injection 500 Mg

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Product Details:

Dosage Form Injection (Lyophilized Powder)
Salt Composition Pemetrexed Disodium 500 mg
Indication Non-Small Cell Lung Cancer, Malignant Pleural Mesothelioma
Feature
Ingredients Pemetrexed Disodium, Mannitol, Hydrochloric Acid and/or Sodium Hydroxide (for pH adjustment)
Application Intravenous use only
Ph Level Between 6.6 and 7.0 (after reconstitution)
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Pemetrexed Injection 500 Mg Price And Quantity

Minimum Order Quantity 100 Bottle

Pemetrexed Injection 500 Mg Product Specifications

Salt Composition Pemetrexed Disodium 500 mg
Dosage Form Injection (Lyophilized Powder)
Ph Level Between 6.6 and 7.0 (after reconstitution)
Application Intravenous use only
Ingredients Pemetrexed Disodium, Mannitol, Hydrochloric Acid and/or Sodium Hydroxide (for pH adjustment)
Fermentation Smell Odorless
Indication Non-Small Cell Lung Cancer, Malignant Pleural Mesothelioma
Storage Instructions Store below 25C, protect from light
Physical Color/Texture White to light yellow lyophilized powder
Shelf Life 24-36 months (as per pack label)

Diluent Required Sterile sodium chloride injection, USP
Marketing Authorization Holder Varies by distributor/manufacturer
Reconstitution To be reconstituted with 0.9% Sodium Chloride Injection prior to intravenous administration
Additional Note Further dilution may be required prior to administration depending on the total dose prescribed.
NDC or Product Code Provided on packaging (may be specific to manufacturer/distributor)
Contraindications Known hypersensitivity to Pemetrexed or excipients
Box Dimensions Typically 8 x 5 x 3 cm (may vary by manufacturer)
Strength 500 mg/vial
Manufacturing Standard Manufactured under GMP guidelines
Patient Population Adults only
Pack Size Single-use vial
Prescription Status Prescription only medication
Administration Route Intravenous (IV) infusion only
Barcode/Batch Information Available on vial and outer carton

Product Description

Pemetrexed injection is used in combination with other chemotherapy medications as a first treatment for a certain type of non-small cell lung cancer (NSCLC) that has spread to nearby tissues or to other parts of the body. Pemetrexed injection is also used alone to treat NSCLC as ongoing treatment in people who have already received certain chemotherapy medications and whose cancer has not worsened and in people who could not be treated successfully with other chemotherapy medications. Pemetrexed injection is also in combination with another chemotherapy medication as a first treatment for malignant pleural mesothelioma (a type of cancer that affects the inside lining of the chest cavity) in people who cannot be treated with surgery. Pemetrexed is in a class of medications called antifolate antineoplastic agents. It works by blocking the action of a certain substance in the body that may help cancer cells multiply.

What is Pemetrexed Injection 500 mg used for?

Pemetrexed Injection 500 mg is prescribed to adult patients for the treatment of non-small cell lung cancer and malignant pleural mesothelioma. This antineoplastic agent acts as a cytostatic chemotherapy drug, impeding cancer cell proliferation. It is administered under strict medical supervision and forms part of a comprehensive cancer care regimen.

How is Pemetrexed Injection prepared and administered?

Before administration, the lyophilized powder must be reconstituted with 0.9% Sodium Chloride Injection, USP. Following reconstitution, further dilution may be needed based on the total dosage required. The solution is then delivered via intravenous infusion only. Proper preparation and administration should be carried out by healthcare professionals in a clinical setting.

What are the storage and handling requirements?

Pemetrexed Injection should be stored at temperatures below 25C and kept protected from light. The shelf life typically spans 24 to 36 months as indicated on the package label. Always ensure the vial is intact, and barcode or batch information is checked before use to guarantee product integrity and traceability.

FAQ's of Pemetrexed Injection 500 Mg:

Q: How should Pemetrexed Injection 500 mg be reconstituted and administered?

A: Pemetrexed Injection 500 mg should be reconstituted using 0.9% Sodium Chloride Injection, USP. After dissolving the lyophilized powder, additional dilution may be necessary to achieve the prescribed dose. The final solution is then administered exclusively through intravenous infusion by a qualified healthcare provider.

Q: What is the recommended storage condition for Pemetrexed Injection vials?

A: The vials should be stored below 25C and kept away from direct light. Ensure the product remains in its original packaging until ready for use to maintain stability and effectiveness throughout its 24-36 month shelf life.

Q: Who is eligible to receive Pemetrexed Injection 500 mg?

A: This medication is intended for adult patients only and is prescribed for conditions such as non-small cell lung cancer and malignant pleural mesothelioma. It should not be used in children or individuals with known hypersensitivity to Pemetrexed or its excipients.

Q: Where can batch or product code information be found on the packaging?

A: Batch and barcode information, as well as the NDC or product code, are printed on both the vial and the outer carton. This ensures easy identification and traceability for distributors, healthcare providers, and pharmacies.

Q: What are the key benefits of Pemetrexed Injection 500 mg for patients?

A: Pemetrexed Injection offers a proven treatment option for specific cancers by inhibiting cell replication, aiding disease management, and potentially improving patient outcomes when used as part of a doctor-managed chemotherapy regimen.

Q: Is a prescription required to obtain Pemetrexed Injection 500 mg?

A: Yes, this product is classified as a prescription-only medication. It should only be used under the direction and supervision of an oncologist or qualified healthcare professional.

Q: What should I do if I am allergic to Pemetrexed or any of the listed ingredients?

A: If you have a known hypersensitivity to Pemetrexed, Mannitol, Hydrochloric Acid, Sodium Hydroxide, or any excipients in the formulation, you must inform your healthcare provider. The injection is contraindicated in such cases, and alternative treatments should be considered.

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